Entries by Mehmet Kazgan

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cliexa Partners with Lucem Health to bring its Opioid Use Disorder Prediction Platform to the Point of Care

 

Denver, CO – cliexa announces a strategic partnership with Lucem Health providing expert support and an innovative platform to help deploy and commercialize cliexa’s Opioid Use Disorder Prediction Platform in clinical settings.

 

Pain management teams must overcome significant complexity to deliver effective clinical care to opioid patients, including, managing the interplay of multiple, chronic medical conditions, behavioral health issues, and intricate medication management. This onerous process places unnecessarily high cognitive loads-on clinicians that increase the risk of burnout.

 

cliexa platform empowers pain management teams with the right data, at the right time, directly within the workflow of electronic medical records, freeing up clinic staff’s cognitive space, and enabling clinicians to make the best choice for the patient sitting in front of them.    

 

cliexa recently completed Mayo Clinic Platform-Accelerate and announced its Opioid Use Disorder Prediction Model trained with de-identified patient data provided by the Mayo Clinic Platform. cliexa also worked with technology experts from Google to ensure the highest standards of transparency and minimize bias.

 

cliexa and Lucem Health will work together and identify technical enablement and commercialization processes as well as anticipated ROI for cliexa’s predictive model in clinical settings. Lucem Health will assist cliexa by adding further insights to end users, taking cliexa’s AI model, and putting it in context for the appropriate end users.

 

“Right after our recent launch of Opioid Use Disorder Machine Learning Algorithms, Lucem Health partnership will be further verification of our platform, especially for commercialization stage and improve our delivery with industry experts. We feel extremely lucky and excited for this partnership opportunity.” Said, Mehmet Kazgan, Founder and CEO of cliexa.

 

“The Innovation Collaborative helps AI/ML and Digital Health innovators create, deploy, and commercialize clinical AI solutions that transform care,” says Sean Cassidy, CEO, Lucem Health. “Our partnership with cliexa is further testament of our continually growing partner network, and the wealth of possibilities it provides to our customers.”

“We are very pleased to see cliexa, the graduate of the first Accelerate cohort, receive support from Lucem, a Mayo Clinic Platform portfolio company,” says Eric Harnisch, vice president, Partner Programs, Mayo Clinic Platform.

 

About cliexa:

cliexa, Denver-based digital health firm, developed an end-to-end virtual health platform that provides clinicians a complete understanding of real-time patient data. cliexa removes the barriers and inaccuracies in data collection, empowering clinicians to provide personalized care. cliexa partnered with industry-leading organizations like Mayo Clinic and the American College of Cardiology to validate its patented technology powered by AI to change patients’ lives.

About Lucem Health:

Lucem Health™, launched with Mayo Clinic along with investing partners Commure (a General Catalyst company) and Rally Ventures, empowers healthcare visionaries to quickly bring AI-powered insights to the point of care. Digital health innovators develop transformative clinical solutions and advance them from the bench to the bedside to the front lines of healthcare on a single integration platform. Visionary clinical leaders deploy novel data and insights seamlessly into clinical workflows while ensuring that clinicians trust, adopt, and see value in them. For more information, visit www.lucemhealth.com.

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cliexa joins Mayo Clinic Platform Accelerate!

cliexa joined Mayo Clinic Platform_Accelerate, an immersive program for health tech startups as part of its initial cohort of participating companies.

The program offers cliexa access to Mayo Clinic experts in regulatory, clinical, technology and business domains with a focus on AI model validation and clinical readiness. Technology experts from Google and Epic also will provide workshops.

"Health tech startups are critical contributors to the cycle of innovation," says John Halamka, M.D., president of Mayo Clinic Platform, a strategic initiative to improve health care through insights and knowledge derived from data. "We are excited to collaborate with these innovators to solve some of the most complex problems in medicine today."

cliexa will:

  • Work with data science experts to delineate AI model requirements.
  • Check for fairness and bias in their AI models.
  • Gain understanding of Food and Drug Administration clearance pathways.
  • Access de-identified Mayo Clinic patient data in a secure environment.
  • Conduct model validation with guidance from data science experts.
  • Plan clinical validation studies, such as clinical simulation or clinical trials.
  • Explore eligibility to partner with Mayo Clinic Platform.

"We are helping participants take a crucial step in their growth trajectory by providing startups with a disciplined focus on model validation and clinical readiness to show product value," says Eric Harnisch, Vice President of Partner Programs for Mayo Clinic Platform. "The program is integral to our Mayo Clinic Platform mission to enable new knowledge, new solutions and new technologies that improve patients' lives worldwide."

Read more at Mayo Clinic News Network Press Release here.

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About Mayo Clinic Platform
Founded on Mayo Clinic's dedication to patient-centered care, Mayo Clinic Platform enables new knowledge, new solutions and new technologies through collaborations with health technology innovators to create a healthier world. To learn more, visit the Mayo Clinic Platform website.

About Mayo Clinic
Mayo Clinic is a nonprofit organization committed to innovation in clinical practice, education and research, and providing compassion, expertise and answers to everyone who needs healing. Visit the Mayo Clinic News Network for additional Mayo Clinic news.

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cliexa, Integrated Care Technology Solutions Provider, Announces the Appointment of Ajit Dhaliwal, MD as Chief Growth Officer

Dr. Dhaliwal, who recently joined cliexa’s executive management team will be leading strategic growth at cliexa. Dr. Dhaliwal, is a physician entrepreneur, has been serving as CEO of Momentum Healthcare Staffing, board member of two VC funds and other healthcare startups. Dr. Dhaliwal also served as the Associate Medical Director of Prognos Health. With his […]

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Patient Education with Evidence-based Infographics

University of Colorado College of Nursing Partners with cliexa to Launch a Mobile Application with Evidence-based Infographics

HIV disproportionately affects Latinos who experience higher prevalence, faster disease progression, more HIV-related deaths, and a marked delay in diagnosis and treatment than their white counterparts. This is a concern in geographic regions across the United States (US) as Latinos comprise the largest minority group in the US. Similar HIV-related health disparities exist in developing countries, such as the Dominican Republic (DR), where those with low socioeconomic status experience higher disease burdens and worse outcomes than those with higher socioeconomic status. These health disparities are exacerbated when affected individuals have low health literacy and are unable to understand the information needed for self-management, as inability to self-manage leads to less use of healthcare services and worse understanding of illness, health behaviors, and health outcomes.  Therefore, to improve health outcomes and reduce health disparities among Latino persons living with HIV (PLWH), clinicians must provide the health information needed for effective self-management to diverse Latino PLWH in a meaningful way.

In response to these concerns, Dr. Samantha Stonbraker, Assistant Professor at the University of Colorado College of Nursing, rigorously and iteratively developed the Info Viz for Health intervention to assist clinicians to provide this health information to PLWH through several NIH-funded studies. She first identified a need for this intervention (T32 NR013454).1-3 Then, she worked with an expert visualization team at Columbia University in New York and with health care providers and PLWH at a clinic in the Dominican Republic to develop a set of culturally relevant and evidence-based infographics to assist clinical communication (T32 NR007969).4, 5 She has since assessed the feasibility of using the Info Viz for Health intervention to improve clinical communication with, and outcomes of, PLWH in the DR.6, 7 She also adapted infographics to the cultural and clinical context of Latino PLWH living in New York (NY), who are mainly of Dominican origin/descent and also assessed their feasibility and acceptability at a clinic specializing in HIV care in Northern Manhattan (K99 NR017829).

Two critical next steps in this work were:

  • To adapt Info Viz for Health for relevance to heterogeneous Latino populations across the US by adapting them to Latinos of Mexican origin/descent as these individuals form the largest Latino group in the US and their inclusion is necessary to enhance generalizability and enable future scalability of the intervention. To do this, Dr. Stonbraker conducted a series of in-depth interviews with PLWH attending a clinic that specializes in HIV care in Denver, CO, and adapted the infographics accordingly.
  • To integrate the Info Viz for Health infographics into a mobile platform to enable ease of use and scalability. Dr. Stonbraker teamed up with cliexa, an innovative company that develops and creates digital health solutions. Together, they incorporated the Info Viz for Health into a mobile app that is now accessible on the App Stores both in Apple and Google in English and Spanish languages.

Currently, Dr. Stonbraker is conducting a multi-site randomized controlled trial (RCT) to evaluate the efficacy of using the Info Viz for Health app to improve clinical communication and treatment outcomes of Latino PLWH at clinical sites in CO and the DR. Seven providers at the two different clinical sites are using the Info Viz for Health app as a communication aid while they provide information to study participants.

The research aims of this project are to:

Aim 1 Assess the efficacy of the intervention as compared to standard care in improving treatment outcomes (CD4 count, viral load, self-efficacy to manage HIV, among others) of PLWH and determine how resultant effects vary over time (baseline to 9-months) and between sites.

Aim 2 Evaluate the feasibility, acceptability, and usability of the app among interdisciplinary and multi-cultural providers using the app.

Aim 3 Identify implementation factors of integrating the mobile app into electronic health records (HER) through in-depth interviews and leverage findings to ensure the app effectively interfaces with EHRs in the US and DR.

Next steps:

  • Health care providers at all sites where infographics have been used have requested additional infographics be incorporated into the app so that they can address additional topics with their patients. Dr. Stonbraker will conduct a needs assessment to identify the pertinent topics to include next and will create rigorously designed and culturally appropriate infographics in response to identified needs.
  • The Info Viz for Health app is provider-facing and would benefit from integration with EHRs. Therefore, the next step in app development is to integrate it with Fast Healthcare Interoperability Resources (FHIR)®, which is the standard for connecting mobile apps and electronic health records (EHR). This permits scalability, as the resultant app enables clinicians to easily access evidence-based infographics from diverse settings globally.

The final product will be an app that interfaces with EHRs in resourced and under-resourced areas globally, has been rigorously tested amongst diverse Latino PLWH in distinct geographic settings in multiple languages, and includes evidence-based infographics to facilitate the clinical communication that helps patients improve their self-management and obtain better health.

References

 

  1. Stonbraker S, Smaldone A, Luft H, et al. Associations between health literacy, HIV-related knowledge, and information behavior among persons living with HIV in the Dominican Republic. Public Health Nurs. 2017;35(3):166-175. doi:10.1111/phn.12382
  2. Stonbraker S, Befus M, Lerebours Nadal L, Halpern M, Larson E. Factors associated with health information seeking, processing, and use among HIV positive adults in the Dominican Republic. AIDS Behav. 2016;21(6):1588–1600. doi:10.1007/s10461-016-1569-5
  3. Stonbraker S, Larson E. Health-information needs of HIV-positive adults in Latin America and the Caribbean: an integrative review of the literature. AIDS Care. 2016;28(10):1223-1229. doi:10.1080/09540121.2016.1173645
  4. Stonbraker S, Halpern M, Bakken S, Schnall R. Special Section on Visual Analytics in Healthcare: Developing infographics to facilitate HIV-related patient-provider communication in a limited-resource setting. Appl Clin Inform. 2019;10:597-609. doi:10.1055/s-0039-1694001
  5. Stonbraker S, Richards SD, Halpern M, Bakken S, Schnall R. Priority topics for health education to support HIV self-management in limited-resource settings. J Nurs Scholarsh. 2019;51(2):168-177. doi:10.1111/jnu.12448
  6. Stonbraker S, Flynn G, George M, et al. Feasibility and acceptability of using information visualizations to improve HIV-related communication in a limited-resource setting: A short report. AIDS Care. In Press;doi:10.1080/09540121.2021.1883517
  7. Stonbraker S, Liu J, Sanabria G, et al. Clinician Use of HIV-Related Infographics During Clinic Visits in the Dominican Republic is Associated with Lower Viral Load and Other Improvements in Health Outcomes. AIDS Behav. In Press:1-13. doi:10.1007/s10461-021-03331-8

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American College of Cardiology, cliexa Launch Innovative Health Monitoring Platform

American College of Cardiology, cliexa Launch Innovative Health Monitoring Platform The American College of Cardiology and cliexa, have collaborated through the ACC Innovation Program to launch a home health monitoring platform called cliexa-PULSE. ” cliexa-PULSE is a revolutionary app and platform that allows cardiovascular clinicians to gather information from their patients before and after visits to […]